Menstrual health matters

Why the “cortisol (pregnenolone) steal” hypothesis is incorrect

Why the “cortisol (pregnenolone) steal” hypothesis is incorrectBy: Fiona Catchpowle Published on: 26/08/2025

The popular story says: under stress the adrenals “steal” pregnenolone to make cortisol, leaving too little substrate for DHEA and the downstream sex hormones. It’s tidy—and wrong.

Menstrual Health Biology
Why the “cortisol (pregnenolone) steal” hypothesis is incorrect

free practitioner download

The Ovary User Guide

Made for More that Periods & Perimenopause

Start making a real impact today.

Why You Need This

The Ovary User Guide is a short, sharp, 5-minute read designed to:.

  • Uncover quick, memorable facts about ovarian function you can use instantly to spark insight and better client conversations.

  • Give an eye-opening snapshot of the ovaries’ physical features, functions, and rhythms.

Our Mission

Decades of incomplete information has left a legacy of misunderstandings that are affecting health outcomes on a global scale. We will create a worldwide collective of menstrual and menopause health informed professionals so every menstruator has the knowledge and support to take their next best step as they travel along the menstrual health timeline.

© Copyright 2025 Made in Brum, UK. All Rights Reserved.